Detail Koleksi
KADAR ANTIBODI IgG SARS COV-2 SETELAH VAKSINASI COVID-19 DOSIS LANJUTAN
| Penulis | Fajrunni'mah, Rizana; Purwanti , Angki; Setiawan, Budi |
|---|---|
| Sumber | Media Penelitian dan Pengembangan Kesehatan |
| Jenis | Jurnal |
| Tahun | 2023 |
| Volume | 33 |
| Nomor | 2 |
| Penerbit | Poltekkes Kemenkes Bandung |
| Abstrak | COVID-19 is a problem throughout the world, including Indonesia. One of the efforts to overcome the COVID-19 pandemic is vaccination. A follow-up or booster dose was needed to increase individual protection because there was a decrease in antibodies 6 months after receiving vaccination. This study aimed to determine SARS-CoV-2 IgG antibody levels before and after 8 months of the third booster vaccination. This research method was observational with a longitudinal, cohort approach to 27 samples using a consecutive sampling technique at the Health Polytechnic of the Ministry of Health, Jakarta III in April-November 2022. The data collection techniques used questionnaires and venous blood sampling to examine quantitative Anti-SARS CoV-2 Ig G levels using the CMIA (Chemiluminescent microparticle immunoassay) method with the Architect tool which was carried out twice, namely before administration and 8 months after the third booster vaccination with a heterologous vaccine. Data were analyzed using a statistical test of the difference between the means of two groups. Based on the research results, although statistically there was no significant difference between before and 8 months after vaccination (p=0.055), there was a decrease in the mean quantitative Anti-SARS CoV-2 IgG level of 5301.24 AU/mL. As many as 63% of subjects experienced a decrease in antibody levels 8 months after vaccination compared to before the third booster vaccination. Longitudinal studies are needed to determine protective antibody levels. |
| DOI | 10.34011/jmp2k.v33i2.1865 |
| URL Sumber | Lihat Sumber |
| 📊 Statistik Kunjungan | ✅ Total dilihat: 10 kali 👥 Pengunjung unik: 10 orang |